Growing up as a research subject: ethical and legal issues in birth cohort studies involving genetic research.
نویسنده
چکیده
Introduction Many population genetic research projects seek to recruit women during pregnancy or infants at birth for longitudinal birth cohort studies that investigate how early environmental conditions interact with a child’s genome to increase disease susceptibility or confer protective effects. Researchers worldwide are sleuthing for genetic factors related to major child health problems such as obesity, diabetes, behavioural disorders, allergies and asthma. These research initiatives depend on the availability of biological samples collected periodically from children, their mothers and sometimes other family members – often including samples of blood, placenta, hair, nails and urine – and collection of information about lifestyle, environmental exposures and health. One commentator observes:
منابع مشابه
Handling ethical, legal and social issues in birth cohort studies involving genetic research: responses from studies in six countries
BACKGROUND Research involving minors has been the subject of much ethical debate. The growing number of longitudinal, pediatric studies that involve genetic research present even more complex challenges to ensure appropriate protection of children and families as research participants. Long-term studies with a genetic component involve collection, retention and use of biological samples and per...
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عنوان ژورنال:
- Health law journal
دوره 15 شماره
صفحات -
تاریخ انتشار 2007